… Of note, the use of proteasome inhibitors, such as bortezomib… of mutation affecting prognosis,
being related to anthracycline … Multidrug resistance (MDR) efflux transporters of the ABC (…

… cytarabine and anthracycline as 7 days of standard dose of … mechanisms of multidrug
resistance (MDR) in malignant … Rapamycin demonstrated anti-leukemic activity in relapsed AML, …

… We established nuclear FOXM1 as an independent clinical … Induction therapy included
cytarabine and an anthracycline in … therapeutic benefit by adding bortezomib to cytarabine-based …

… apoptosis in BJAB cells occurs independently of CD95/Fas … cytarabine resulted in a synergistic
effect, with apoptotic cells … of resistances, including to the Vinca alkaloids, anthracyclines…

… Interestingly, the number and activity of proteasomes is … asked if the HME status was an
independent predictor of outcome. … cell counts after cytarabine therapy between cells cultured in …

… may be attributed to faulty upregulation or mutation of multiple drug resistance … : anthracycline
topoisomerase inhibitor Multiple Myeloma 30 mg/m 2 IV on day 4 following bortezomib …

… -dose chemotherapy with anthracyclines and vincristine in … cytarabine and doxorubicine
activity in p53 wild type cells [72]. … of resistant clones we decided to associate bortezomib (1.3 mg…

… for normal cell metabolism, bortezomib drives the cell to apoptotic … Anthracyclines exhibit
anti-proliferatory effects in the … as acute lymphoblastic leukemia and acute myeloid leukemia, …

… drugs such as glucocorticoids or anthracycline (29,30). HSC … following drugs: Cytarabine,
methotrexate, anthracyclines and … relapse is associated with multiple drug resistance (MDR) (90…

… , camptothecins, bisantrene, anthracyclines, and flavopiridol … be responsible for bortezomib
resistance in multiple myeloma… promoting resistance to cytarabine in acute myeloid leukemia…